IAB Research Project Description

Central Nervous System Regulation of Metabolic Suppression for Combat Casualty Care

Arctic ground squirrel in wood shavings. Credit: Lesa Hollen and Leone Thierman

Franziska Kohl, Institute of Arctic Biology research professional, checks traps for arctic ground squirrels on Alaska's North Slope. Credit: Oivind Toien/IAB

Any and all uses of these images must include photographer credit.

We propose to investigate neurotransmitter-regulated mechanisms of metabolic suppression in hibernating Arctic ground squirrels (AGS). Results from prior work have begun to identify brain regions, including the suprachiasmatic nucleus (SCN) with metabolic activity during torpor or early arousal thermogenesis and have developed the instrumentation to monitor glutamate release in these regions. Thus, the proposed studies are designed to test the hypotheses that glutamate release in the SCN of hibernating animals coordinates hibernation.

Project Funding

U.S. Dept. of Defense Experimental Program to Stimulate Competitive Research
$304,817.00
31 May 2005 – 30 Apr 2008
IAB Proposal #05-019
UAF Grant #G2551
IAB Project #84


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